Laboratory Safety Manual
B. Process Planning
Working safely in the laboratory does not happen by accident. Planning
laboratory processes will help you identify hazards, establish hazard
control measures, and ultimately keep you and other lab personnel
Standard Operating Procedures
Process planning must begin with each investigator or laboratory
group completing hazard assessments and developingstandard operating procedures
(SOPs). The purpose of a hazard assessment
is to identify and evaluate all chemical, biological, radiological, and
physical hazards associated with laboratory operations and describe
safety precautions necessary to avoid employee exposures and
SOPs must be specific to each laboratory operation.
SOPs must be reviewed and approved by the Principal Investigator
(PI) or the laboratory supervisor. After approval, SOPs are then
incorporated into or attached to written materials and methods.
Laboratory personnel must be trained on the elements of the SOP
before performing an experiment or operation. At a minimum, SOPs
must include the following:
• Health and safety information for materials used
and briefly describe the chemical, biological, radiological,
and physical hazards associated with the operation. Identify
available resources likesafety data sheets (SDS)
where they can be accessed.
• Hazard control measures
– include containment devices,
ventilation, specific personal protective equipment, and hygiene
practices as recommended by the SDS or other authoritative
guide. Evaluate whether special procedures discussed below
will be required.
• Waste disposal practices
– establish procedures for the safe
and timely removal of laboratory waste. ReferenceSection H, “Waste and Recycling,
” as appropriate or develop written
procedures if necessary.
• Decontamination procedures
– develop procedures and
include required frequency and duration.
• Spill/release containment and clean up procedures
develop procedures using Section C, “Emergency Planning” of
SOPs must be readily available in the laboratory where the experiment
or operation will be performed and should be reviewed and updated