Biosafety Manual 4 Table of Contents Directory of Service and Emergency Providers 3 A. Introduction 7 Definition of Biohazardous Materials 7 Purpose 7 Responsibilities 8 Iowa State University (ISU) 8 Environmental Health and Safety (EH&S) 8 Supervisors 8 Personnel 8 Institutional Biosafety Committee (IBC) 8 B. Recombinant or SyntheticNucleicAcidMolecules, Human,Animal, andPlant Pathogens, Biological Toxins: Institutional Biosafety Committee (IBC) 10 C. Medical Survelliance 12 Workplace Exposure Assessment 12 Exposure Monitoring 12 Vaccinations and Testing 13 Exposure to Biohazardous Materials 13 Work-Related Injuries, Illnesses and Exposures 14 Reporting 14 D. Biosafety Practices and Procedures 16 Work Practices (First Line Of Defense) 16 Laboratory Biosafety Level Criteria 16 Biosafety Level 1 (BSL–1) Minimum Criteria 18 Biosafety Level 2 (BSL–2) Minimum Criteria 19 Biosafety Level 3 (BSL–3) Minimum Criteria 20 Biosafety Level 4 (BSL–4) 21 Laboratory Decommissioning 22 Training and Education 22 Signs and Labeling 23
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