8 Biosafety Manual Responsibilities Iowa State University (ISU) The president of Iowa State University is ultimately responsible for all environmental, health and safety issues. This responsibility is exercised through the normal lines of authority within the university by delegating the charge for ensuring safe work practices and adherence to established policies and guidelines to the senior vice president and provost, deans, directors, department chairs, principal investigators, supervisors, and, ultimately, each employee. Environmental Health and Safety (EH&S) EH&S is responsible for the development and oversight of proper management practices for all biohazardous materials at Iowa State University, including developing and implementing policies for ISU. EH&S is also responsible for ensuring that affected departments are aware of the university policies and regulatory guidelines regarding the proper use of biohazardous materials. Supervisors Principal Investigators (PIs), instructors, and supervisors are primarily responsible for ensuring that the policies and guidelines established in this manual are strictly followed by all personnel under their jurisdiction, including collaborating researchers. Personnel Individuals who work with biohazardous materials have a responsibility to follow the guidelines presented in this manual and to consult with their supervisors regarding the safe handling and proper disposal of specific biohazardous materials used in their work area. Individuals who are pregnant, immunocompromised, or have other health conditions are advised to consult the safety data sheets (SDS) for all hazardous chemicals, radioactive materials, and pathogenic organisms in their workplace environment in order to determine if any risks exist. They should also consult with their supervisor, Occupational Medicine, or their physician of choice concerning potential risks and how to manage those risks.