11 Laboratory Safety Manual Environmental Health and Safety Special Procedures Special procedures must be developed for work involving materials or equipment that present a significant risk of exposure or injury to the human body. Examples include carcinogens, reproductive toxins, teratogens, highly toxic substances, explosives, controlled substances, select biological agents, radioactive materials, radiation producing devices, and lasers. The following special procedures must be developed and specified on the SOP: • Identify authorized personnel who are permitted to work with these materials or equipment. Authorized persons must receive training on the unique hazards of these materials or equipment before use. • Establish a designated area for a specific use (fume hood, glove box, lab bench, etc.) and identify the area by signs or postings. Restrict access to this area to authorized personnel. If an entire laboratory is designated, then access must be restricted to authorized personnel. • Specify special safety precautions for experiments or laboratory operations where these materials or equipment are used. Be sure to identify specialized equipment, shielding, or security requirements to be used. Additional Resources • Carcinogens, Reproductive Toxins and Teratogens • Laser Safety Manual • Radioactive Materials Safety Manual • Sealed Source Safety Manual • Select Biological Agents and Toxins • X-Ray Safety Manual Use of Engineering Controls Engineering controls must be implemented where and when possible, to reduce hazards associated with the use and storage of chemical, biological, and radiological materials. Engineering controls should be considered in the following order: • substitution of less hazardous equipment, chemicals, or processes • physical isolation of the operator or process (fume hood, blast shield, glove box, etc.) • local and general exhaust ventilation and/or filtration (use of fume hoods, charcoal filters, etc.) Note: Many high risk materials or equipment require special authorization from EH&S or a government agency to purchase, possess and use. Refer to the “Ordering Chemical, Biological and Radioactive Materials” Section below for information on the application process for each material.