39 Laboratory Safety Manual Environmental Health and Safety • Read and understand the Radiation Safety Rules Notice to Workers and Notice to Employee laboratory signs. • Read and understand the emergency contact information posted at entrances to the laboratory. • Maintain the security of all radiation machines, radioactive materials including labeled materials, equipment, and waste. • Label locations within the laboratory where radionuclides are used or stored (hoods, refrigerators, microwave ovens, etc.) to indicate the presence of radioactive material. Additional Resources • Radiation Safety Guide for Ancillary Personnel Particularly Hazardous Substances Particularly hazardous substances include select carcinogens, reproductive toxins, and chemicals with a high degree of acute toxicity. Some examples of chemicals with a high level of acute toxicity include dimethyl mercury, hydrogen cyanide, hydrogen fluoride, and osmium tetroxide. The following special procedures must be developed and specified on the SOP when working with particularly hazardous substances: • Identify authorized personnel who may work with these materials or equipment. Authorized persons must receive training on the unique hazards of these materials or equipment before use. • Establish a designated use area (fume hood, glove box, etc. ) and identify the area by signs or postings. Restrict access to this area to authorized personnel. If an entire lab is designated, then access must be restricted to authorized personnel. • Specify special safety precautions for experiments or laboratory operations where these materials or equipment are used. Be sure to identify specialized equipment, shielding, or security requirements to be used. List of carcinogens, reproductive toxins, and teratogens. Water Reactives • Water reactive materials combine with water or moisture in the air to spontaneously ignite or produce flammable or toxic gases. Examples include metals such as sodium and potassium, acid anhydrides and acid chlorides, and fine metal powders, such as zinc. • Handle away from water sources. • Use in well ventilated area or inert atmosphere.